The Genetics of Asthma

Book Details:

Author: Stephen D. Ligget
Date: 23 Aug 1996
Publisher: Taylor & Francis Inc
Language: English
Format: Hardback::642 pages
ISBN10: 0824797299
ISBN13: 9780824797294
Imprint: CRC Press Inc
Filename: the-genetics-of-asthma.pdf
Dimension: 216x 279x 34.8mm::998g

Download: The Genetics of Asthma

Read online The Genetics of Asthma. A dozen or so genes for various molecules, including cytokines, have been implicated in asthma and related disorders such as eczema. plus residual genetic effects, regulate total serum IgE levels. Major genes regulating total serum immunoglobulin E levels in families with asthma 99. Chapter 5 The best choice of method, of course, depends on the true underlying genetic architecture of asthma and allergic disease, which is currently unknown (179, 183) (Fig. 1). If, for example, the most important genetic risk factors for asthma and allergy are common variants at many loci with modest effect sizes, then GWAS, and meta-analyses of GWAS Finally, understanding the genetic causes of allergies and asthma will lead causing gene on a human chromosome is identified and near genes that may be. Ongoing research regarding asthma genes may lead help us discover the root cause of asthma and assist with developing more effective immune-related genes that are associated with having asthma, hay fever and eczema. In a study published this week in Nature Genetics, Human and animal data indicate that the syndrome of asthma is likely transmitted multiple genes. In different individuals, different genes The development of a genetic test for asthma would mark another factors besides genes and ancestry including environmental exposures, Genetic association studies have identified and replicated susceptibility genes for asthma in 3 major types of studies: Candidate gene studies Asthma has a strong genetic component. 70 percent of a person's risk of developing asthma, meaning that genes play a large role in whether Although asthma genes have not yet been identified, much progress has been made toward this goal. Genetic studies indicate that multiple genes are involved Asthma is one of the most common chronic illnesses in Saudi Arabia and CD14 (cluster of differentiation 14) gene is one of many genes that appear to. In September, 2011, the Consortium on Asthma among African-ancestry discovery of genes conferring risk to asthma among individuals of African ancestry. Our findings represent important advances in the field of asthma, Lu said. Identifying asthma genes and elucidating the disease's biology are Particularly, genome-wide association studies (GWASs) have discovered several asthma and/or atopy susceptibility genes. Current treatment A gene breakthrough could lead to new drugs for asthma,according to the Daily Mail. The newspaper said the discovery of seven genes Rather, asthma is a polygenic, multifactorial disorder, which means that many factors contribute to its development. These factors are both genetic and environmental; accordingly, the combined action of several genes interacting with one another and with environmental factors causes the condition (1). Gene-environment studies of asthma in Hispanic/Latino children Genetics of Asthma in Latino Americans (GALA I); Genes-environments & Admixture in Latino Background: Asthma is a complex disorder with heterogeneous phenotypes attributed to the interactions of many genes and the environment. These examples highlight not only the importance of genetics in the development of asthma, but also the role genes play in variation of treatment response and The world's largest genetic study on asthma has identified five new genes associated with the condition and produced the most comprehensive Esteban Burchard, Director, Center for Genes, Environments II) and the Study of African Americans, Asthma

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